Each year, as we approach our annual efforts to support the Cystic Fibrosis Foundation, we are reminded of the extraordinary generosity, kindness, and faith that you’ve shown over the past two decades. Thanks to your support, the CF community has made remarkable strides — and yet, as you’ll read below, the journey toward a cure is not yet complete.

Megan’s Journey — Strength, Joy, and Hope

It’s hard to believe how far Megan has come. Today, she continues to thrive in the mountains she loves — skiing, mountain biking, running half marathons, teaching (and doing) Pilates. She lives each day with energy, determination, and gratitude for the life she has — one that wouldn’t have been possible without the progress made through research funded by supporters like you.

This year brought remarkable news: Megan’s most recent Pulmonary Function Test (PFT) was 91%, a number that would have been unthinkable when she was first diagnosed in 2002. The newest generation of CF therapies continues to make a profound difference in her life — and we are both humbled and hopeful as we watch science transform what was once a fatal childhood disease into one that now allows many to live vibrant adult lives.

But Megan also lives with the daily reality that there is still no cure. She also knows that many others with CF — because of their unique genetic mutations — still cannot benefit from these life-saving therapies. That knowledge fuels her drive to keep fighting, not just for herself, but for every person with cystic fibrosis who still waits for a breakthrough.

Extraordinary Progress — and Why Funding Still Matters

When Megan was diagnosed, the median life expectancy for someone with CF was 28 years. Today, it has doubled to over 56 years. Adults now represent more than 60% of the CF population in the United States — proof that the investments made in research are changing lives.

However, the path to a true cure remains complex and expensive. Developing genetic and gene-editing therapies — which could one day correct the underlying cause of CF — is expected to cost ten times more than traditional drug development. Continued fundraising is essential to make these next-generation treatments possible.

Our Gratitude and Our Hope

We share this update with deep appreciation for the role you’ve played in Megan’s journey — and in the progress of thousands of others living with cystic fibrosis. Every donation, every kind word, and every bit of encouragement has made a difference.

If you feel moved to contribute this year, please use the link below. But most importantly, please know how profoundly grateful we are for your friendship, your compassion, and your faith in this fight. Together, we will continue working toward the day when every person with CF can breathe freely — for a lifetime.

With heartfelt thanks and love,

Kim, Dave, Megan and Lizi

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